Isaac's Heart

Isaac's Heart
Familiar #276Quality 0Rebirth

"Protect it"

  • Isaac becomes invincible
  • Spawns a heart familiar that follows Isaac
  • The heart charges up when Isaac fires and releases a burst of tears when he stops
  • ⚠ If the heart familiar gets hit, Isaac takes damage

Found in pools

Treasure Room×1.0Ultra Secret Room×1.0

Unlock

"Isaac's Heart" has appeared in the basement

Starting item in challenges

The Guardian
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